2008

Angelow A, Schmidt M, Weitmann K, Schwedler S, Vogt H, Havemann C, Hoffmann H.
Methods and Implementation of a Central Biosample and Data Management in a Three Centre Clinical Study - The German Transregional Collborative Research Centre on Molecular Pathogenesis and Therapy of Inflammatory Dilated Cardiomyopathy.
Methods and Programs in Biomedicine 2008; in press

Antoniak S., Boltzen U. , Riad A., Kallwellis-Opara A., Rohde M., Dörner A., Tschöpe C., Noutsias M., Pauschinger M., Schultheiss H.P. & Rauch U.:
Viral myocarditis and coagulopathy: increased tissue factor expression and plasma thrombogenicity.
J Mol Cell Cardiol: 45(1) 118-26, 2008

Block A., Rohde M., Erben U., Hammer M., Hummel M., Blunert K., Schultheiss H.P., Volk H.D. & Noutsias M.:
Impact of cell culture media on the expansion efficiency and T-cell receptor Vbeta (TRBV) repertoire of in vitro expanded T cells using feeder cells.
Med Sci Monit: 14(5) BR88-95, 2008 

Bobbert P., Antoniak S., Schultheiss H.P. & Rauch U.:
Globular adiponectin but not full-length adiponectin induces increased procoagulability in human endothelial cells.
J Mol Cell Cardiol: 44(2) 388-94, 2008 

Duechting A., Tschöpe C., Kaiser H., Lamkemeyer T., Tanaka N., Aberle S., Lang F., Torresi J., Kandolf R. & Bock C.T.:
Human parvovirus B19 NS1 protein modulates inflammatory signaling by activation of STAT3/PIAS3 in human endothelial cells.
J Virol: 82(16) 7942-52, 2008 

Eisenreich A., Boltzen U. , Poller W., Schultheiss H.P. & Rauch U.:
Effects of the Cdc2-like kinase-family and DNA topoisomerase I on the alternative splicing of eNOS in TNF-alpha-stimulated human endothelial cells.
Biol Chem: - -, 2008; in press 

Eisenreich A., Celebi O., Goldin-Lang P., Schultheiss H.P. & Rauch U.:
Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and paclitaxel.
Int Immunopharmacol: 8(2) 307-11, 2008 

Elliott P., Andersson B., Arbustini E., Bilinska Z., Cecchi F., Charron P., Dubourg O., Kühl U., Maisch B., McKenna W.J., Monserrat L., Pankuwelt S., Rapezzi C., Seferovic P., Tavazzi L. & Keren A.:
[Classification of the cardiomyopathies]
Kardiol Pol: 66(5) 533-40, discussion 541-2, 2008 

Elliott P., and on-behalf-of-the-following-co-authors:, Andersson B., Arbustini E., Bilinska Z., Cecchi F., Charron P., Dubourg O., Kühl U., Maisch B., McKenna W.J., Monserrat L., Pankuweit S., Rapezzi C., Seferovic P., Tavazzi L. & Keren A.:
The new European definition of cardiomyopathies: which space for muscle dystrophies? reply.
Eur Heart J: - -, 2008; in press 

Elliott P., and on-behalf-of-the-following-co-authors:, Andersson B., Arbustini E., Bilinska Z., Cecchi F., Charron P., Dubourg O., Kühl U., Maisch B., McKenna W.J., Monserrat L., Pankuweit S., Rapezzi C., Seferovic P., Tavazzi L. & Keren A.:
What do tachycardiomyopathy belong to? Reply.
Eur Heart J: - -, 2008; in press 

Escher F., Kuhl U., Sabi T., Suckau L., Lassner D., Poller W., Schultheiss H.P. & Noutsias M.:
Immunohistological detection of Parvovirus B19 capsid proteins in endomyocardial biopsies from dilated cardiomyopathy patients.
Med Sci Monit: 14(6) CR333-338, 2008 

Fechner H., Sipo I. , Westermann D., Pinkert S., Wang X., Suckau L., Kurreck J., Zeichhardt H., Müller O., Vetter R., Erdmann V., Tschope C. & Poller W.:
Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy.
J Mol Med-Jmm: 86(9) 987-97, 2008 

Goldin-Lang P., Tran Q.V., Fichtner I. , Eisenreich A., Antoniak S., Schulze K., Coupland S.E., Poller W., Schultheiss H.P. & Rauch U.:
Tissue factor expression pattern in human non-small cell lung cancer tissues indicate increased blood thrombogenicity and tumor metastasis.
Oncol Rep: 20(1) 123-8, 2008 

Gutberlet M, Spors B, Thoma T, Bertram H, Denecke T, Felix R, Schultheiss HP, Kuhl U.
Diagnostic Accuracy of Cardiac MRI in Patients with Clinically Suspected Chronic Myocarditis - Association with Immunohistologically Detected Inflammation and Viral Persistance.
Radiology 2008: in press 

Kühl U. , Lassner D., Pauschinger M., Gross U.M., Seeberg B., Noutsias M., Poller W. & Schultheiss H.P.:
Prevalence of erythrovirus genotypes in the myocardium of patients with dilated cardiomyopathy.
J Med Virol: 80(7) 1243-51, 2008 

Landsberger M., Staudt A., Choudhury S., Trimpert C., Herda L.R., Klingel K., Kandolf R., Schultheiss H.P., Kroemer H.K., Völker U. & Felix S.B.:
Potential role of antibodies against cardiac Kv channel-interacting protein 2 in dilated cardiomyopathy.
Am Heart J: 156(1) 92-99.e2, 2008 

Lang C, Sauter M, Szalay G, Racchi G, Grassi G, Rainaldi G, Mercatanti A, Lang F, Kandolf R, Klingel K
Connective tissue growth factor: A crucial cytokine mediating cardiac fibrosis in ongoing enterovirus myocarditis.
J Mol Med 2008 Jan;86(1):49-60.

Lang C, Sauter M, Szalay G, Racchi G, Grassi G, Rainaldi G, Mercatanti A, Lang F, Kandolf R, Klingel K.
Conncetive tissue growth factor: a crucial cytokine-mediating cardiac fibrosis in ongoing enterovirus myocarditis
J Mol Med. 2008 Jan;86(1):49-60.

Lim B.K., Xiong D., Dorner A., Youn T.J., Yung A., Liu T.I., Gu Y., Dalton N.D. , Wright A.T., Evans S.M., Chen J., Peterson K.L., McCulloch A.D., Yajima T. & Knowlton K.U.:
Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart.
J Clin Invest: 118(8) 2758-70, 2008 

Lisewski U., Shi Y., Wrackmeyer U., Fischer R., Chen C., Schirdewan A., Jüttner R., Rathjen F., Poller W., Radke M.H. & Gotthardt M.:
The tight junction protein CAR regulates cardiac conduction and cell-cell communication.
J Exp Med: - -, 2008; in press 

Noutsias M., Rohde M., Block A., Klippert K., Lettau O., Blunert K., Hummel M., Kühl U. , Lehmkuhl H., Hetzer R., Rauch U. , Poller W., Pauschinger M., Schultheiss H.P., Volk H.D. & Kotsch K.:
Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies.
BMC Mol Biol: 9 3, 2008 

Raddatz K, Albrecht D, Hochgräfe F, Hecker M, Gotthardt M.
A proteome map of murine heart and skeletal muscle. 
Proteomics 2008; in press

Riad A., Bien S., Gratz M., Escher F., Westermann D., Heimesaat M.M., Bereswill S., Krieg T., Felix S.B., Schultheiss H.P., Kroemer H.K. & Tschöpe C.:
Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice.
Eur J Heart Fail: - -, 2008; in press 

Riad A., Jäger S., Sobirey M., Escher F., Yaulema-Riss A., Westermann D., Karatas A., Heimesaat M.M., Bereswill S., Dragun D., Pauschinger M., Schultheiss H.P. & Tschöpe C.:
Toll-like receptor-4 modulates survival by induction of left ventricular remodeling after myocardial infarction in mice.
J Immunol: 180(10) 6954-61, 2008 

Riad A., Walther T., Yang J., Altmann C., Escher F., Westermann D., Spillmann F., Schultheiss H.P. & Tschöpe C.:
The cardiovascular influence of interleukin-1 beta on the expression of bradykinin B1 and B2 receptors.
Int Immunopharmacol: 8(2) 222-30, 2008 

Rothe D., Werk D., Dutkiewicz M., Schubert S., Grunert H.P., Zeichhardt H., Erdmann V.A., Fechner H. & Kurreck J.:
Inhibition of picornaviruses by means of RNA interference.
Nucleic Acids Symp Ser (Oxf): (52) 63-4, 2008 

Schultheiss HP, Kühl U
Stand der Diagnostik und und Therapie der inflammatorischen Kardiomyopathie.
Internist (Berl). 2008; in press

Shibata R., Skurk C., Ouchi N., Galasso G., Kondo K., Ohashi T., Shimano M., Kihara S., Murohara T. & Walsh K.:
Adiponectin promotes endothelial progenitor cell number and function.
Febs Lett: 582(11) 1607-12, 2008 

Skurk C., Wittchen F., Suckau L., Witt H., Noutsias M., Fechner H., Schultheiss H.P. & Poller W.:
Description of a local cardiac adiponectin system and its deregulation in dilated cardiomyopathy.
Eur Heart J: 29(9) 1168-80, 2008

Strehl B, Textoris-Taube K, Jäkel S, Voigt A, Henklein P, Steinhoff U, Kloetzel PM, Kuckelkorn U.
Antitopes define preferential proteasomal cleavage site usage.
JBC 2008; in press

Streitz M., Noutsias M., Volkmer R., Rohde M., Brestrich G., Block A., Klippert K., Kotsch K., Ay B., Hummel M., Kühl U. , Lassner D., Schultheiss H.P., Volk H.D. & Kern F.:
NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy.
PLoS ONE: 3(6) e2361, 2008 

Tardos J.G., Eisenreich A., Deikus G., Bechhofer D.H., Chandradas S., Zafar U. , Rauch U. & Bogdanov V.Y.:
SR proteins ASF/SF2 and SRp55 participate in tissue factor biosynthesis in human monocytic cells.
J Thromb Haemost: 6(5) 877-84, 2008 

Van Linthout S, Spillmann F, Riad A, Trimpert C, Lievens J, Meloni M, Escher F, Filenberg E, Demir O, Li J, Shakibaei M, Schimke I, Staudt A, Felix S, Schultheiss HP, De Geest B, Tschöpe C.
Human apolipoprotein A-I gene transfer reduces the development of experimental diabetic cardiomyopathy.
Circulation 2008; in press

Van Linthout S, Seeland U, Riad A, Eckhardt O, Hohl M, Dhayat N, Richter U, Ficher J, Böhm M, Pauschinger M, Schultheiss HP, Tschöpe C.
Reduced MMP-2 Activity contributes to Cardiac Fibrosis in Experimental Diabetic Cardiomyopathy.
Basic Res Cardiol 2008; in press.

Vogelsberg H, Mahrholdt H, Deluigi C, Yilmaz A, Kispert EM, Greulich S, Klingel K, Kandolf R,
Sechtem U.
Cardiovascular magnetic resonance in clinically suspected cardiac amyloidosis. Noninvasive Imaging compared to endomyocardial biopsy.
JACC 2008; 51 :1022-30

Westermann D., Kasner M., Steendijk P., Spillmann F., Riad A., Weitmann K., Hoffmann W., Poller W., Pauschinger M., Schultheiss H.P. & Tschöpe C.:
Role of left ventricular stiffness in heart failure with normal ejection fraction.
Circulation: 117(16) 2051-60, 2008 

Westermann D, Mersmann J, Melchior A, Petrik C, Freudenberger T, Lettau O, Schaefer L, Lüllmann-Rauch R, Jacoby C, Schrader J, Brand-Herrman SM, Young MF, Levkau B, Baba HA, Unger Th, Zacharowski K, Tschöpe C, Fischer JW.
Biglycan is required for adaptive remodelling after myocardial infarction
Circulation 2008; in press


 
2007

Cooper LT, Baughman K, Feldman A, Frustaci A, Jessup M, Kühl U, Levine GN, Narula J, Starling RC, Towbin J, Virmani J.
AHA/ACCF/ESC Joint Scientific Statement: The Role of Endomyocardial Biopsy in the Management of Cardiovascular Disease.
Circulation 2007;116:2216-2233

Kasner M, Westermann D, Steendijk P, Gaub R, Wilkenshoff U, Hoffmann W, Poller W, Schultheiss HP, Pauschinger M, Tschöpe C.
Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: A comparative Doppler-conductance catheterization study.
Circulation 2007, 116(6): 637-647

Noutsias M, Kuehl U, Lassner D, Gross U, Pauschinger M, Schultheiss HP, Gutberlet M.
Images in cardiovascular medicine. Parvovirus-B19-associated active myocarditis with biventricular thrombi.Results of endomyocardial biopsy investigations and cardiac magnetic resonance imaging.
Circulation 2007;115:e378-80

Peng J, Raddatz K, Molkentin JD, Wu Y, Labeit S, Granzier H, Gotthardt M.
Cardiac hypertrophy and reduced contractility in titin kinase deficient hearts.
Circulation 2007; 115(6):743-51

Walther T, Tschoepe C, Sterner-Kock A, Westermann D, Heringer-Walter S, Riad A, Nikolic A, Wang Y, Ebermann L, Siems WE, Bader M, Shakibei M, Schultheiss HP, Dörner A.
Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease.
Circulation 2007; 115(3):333-44

Knöll R, Postel R, Wang J, Krätzner R, Hennecke G, Vacaru AM, Vakeel P, Schubert C, Murthy K, Rana BK, Kube D, Knöll G, Schäfer K, Hayashi T, Holm T, Kimura A, Schork N, Toliat MR, Nürnberg P, Schultheiss HP, Schaper W, Schaper J, Bos E, Den Hertog J, van Eeden FJ, Peters PJ, Hasenfuss G, Chien KR, Bakkers J.
Laminin-alpha4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells.
Circulation 2007 Jul 31;116(5):515-25

Cooper LT, Baughman K, Feldman A, Frustaci A, Jessup M, Kühl U, Levine GN, Narula J, Starling RC, Towbin J, Virmani J.
AHA/ACCF/ESC Joint Scientific Statement: The Role of Endomyocardial Biopsy in the Management of Cardiovascular Disease.
J Am Coll Cardiol 2007;50:1914-1931

Sandek A, Bauditz J, Swidsinski A, Buhner S, Weber-Eibel J, von Haehling S, Schroedl W, Karhausen T, Doehner W, Rauchhaus M, Poole-Wilson P, Volk HD, Lochs H, Anker SD.
Altered intestinal function in patients with chronic heart failure.
J Am Coll Cardiol 2007; 50:1561-9

Staudt A, Eichler P, Trimpert C, Felix SB, Greinacher A.
Fcγ receptors IIa on cardiomyocytes and their potential functional relevance in dilated cardiomyopathy.
J Am Coll Cardiol 2007; 49, 1684-1692

Piorkowski M, Fischer S, Stellbaum C, Jaster M, Martus P, Morguet AJ, Schultheiss HP, Rauch U.
Treatment with ezetimibe plus low-dose atorvastatin compared with higher-dose atorvastatin alone: is sufficient cholesterol-lowering enough to inhibit platelets?
J Am Coll Cardiol 2007 Mar 13;49(10):1035-42

Radke M, Peng J, Wu Y, McNabb M, Nelson OL, Granzier H, Gotthardt M.
Targeted deletion of Titin’s N2B region leads to diastolic dysfunction and cardiac atrophy.
PNAS 2007; 104(9):3444-9

Westermann D, Rutschow S, Jager S, Linderer A, Anker S, Riad A, Unger T, Schultheiss HP, Pauschinger M, Tschoepe C
Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: the role of angiotensin type 1 receptor antagonism.
Diabetes  2007;56(3):641-646

Westermann D, Van Linthout S, Dhayat S, Dhayat N, Escher F, Bucker-Gartner C, Spillmann F, Noutsias M, Riad A, Schultheiss HP, Tschoepe C
Cardioprotective and anti-inflammatory effects of interleukin converting enzyme inhibition in experimental diabetic cardiomyopathy.
Diabetes  2007;56(7):1834-1841

Bien S, Riad A, Ritter CA, Gratz M, Olshausen F, Westermann D, Grube M, Krieg T, Ciecholewski S, Felix SB, Staudt A, Schultheiss HP, Ewert R, Voelker U, Tschoepe C, Kroemer HK
The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy.
Cancer Res 2007;67:10428-10435

Elliott P, Andersson B, Arbustini E, Bilinska Z, Cecchi F, Charron P, Dubourg O, Kuhl U, Maisch B, McKenna WJ, Monserrat L, Pankuweit S, Rapezzi C, Seferovic P, Tavazzi L, Keren A.
Classification of the cardiomyopathies: a position statement from the european society of cardiology working group on myocardial and pericardial diseases.
Eur Heart J 2007 Jan;29(2):270-6

Cooper LT, Baughman K, Feldman A, Frustaci A, Jessup M, Kühl U, Levine GN, Narula J, Starling RC, Towbin J, Virmani J
AHA/ACCF/ESC Joint Scientific Statement: The Role of Endomyocardial Biopsy in the Management of Cardiovascular Disease
Europ Heart J 2007; Dec;28(24):3076-93

Szotowski B; Antoniak S, Goldin-Lang P, Tran Q-V, Pels K, Rosenthal P, Bogdanov VY, Borchert HH, Schultheiss HP, Rauch U
Antioxidative treatment inhibits the release of thrombogenic tissue factor from irradiation- and cytokine-induced endothelial cells.
Cardiovasc Res 2007; 73: 806-12

Deiner C, Shagdarsuren E, Schwimmbeck PL, Rosenthal P, Loddenkemper C, Rauch U, Pauschinger M, Dietz R, Schultheiss HP, Dechend R, Pels K.
Nf-kappab and AP-1 activation is associated with late lumen loss after porcine coronary angioplasty and antiproliferative beta-irradiation.
Cardiovasc Res 2007 Jul 1;75(1):195-204

Textoris-Taube K, Henklein P, Pollmann S, Bergann T, Weisshoff H, Seifert U, Drung I, Mügge C, Sijts A, Kloetzel PM, Kuckelkorn U
The N-terminal flanking region of the TRP2360-368 melanoma antigen determines proteasome activator PA28 requirement for epitope liberation.
J Biol Chem 2007 Apr 27; 282(17):12749-54

Wittchen F §, Suckau L §, Witt H, Skurk C, Lassner D, Fechner H, Sipo I, Ungethuem U, Ruiz P, Pauschinger M, Tschöpe C, Rauch U, Kühl U, Schultheiss HP, Poller W (§ equal contributions)
Genomic Expression Profiling of Human Inflammatory Cardiomyopathy Suggests Novel Therapeutic Targets.
J Mol Med 2007; 85: 253-267 (§ equal contributions)

Wittchen F, Suckau L, Witt H, Skurk C, Lassner D, Fechner H, Sipo I, Ungethum U, Ruiz P, Pauschinger M, Tschope C, Rauch U, Kuhl U,
Schultheiss HP, Poller W
Genomic expression profiling of human inflammatory cardiomyopathy (DCMi) suggests novel therapeutic targets.
J Mol Med 2007;85(3):253-267

Kallwellis-Opara A, Staudt A, Trimpert C, Noutsias M, Kuhl U, Pauschinger M, Schultheiss HP, Grube M, Bohm M, Baumann G, Volker U, Kroemer HK, Felix SB
Immunoadsorption and subsequent immunoglobulin substitution decreases myocardial gene expression of desmin in dilated cardiomyopathy.
J Mol Med 2007; Dec;85(12):1429-35

Bobbert P, Antoniak S, Schultheiss HP, Rauch U
Globular adiponectin but not full length adiponectin induces increased procoagulability in human endothelial cells.
J Mol Cell Cardiol 2007; Nov 28

Fechner H §, Pinkert S §, Wang X, Sipo I, Suckau L, Kurreck J, Dörner A, Sollerbrant K, Zeichhardt H, Grunert H-P, Schultheiss H-P, Poller W (§ equal contributions)
Coxsackievirus B3 and Adenovirus Infections of Cardiac Cells are Efficiently Inhibited by Vector-Mediated RNA Interference Targeting Their Common Receptor.
Gene Therapy 2007; 14: 960-71

Fechner H, Suckau L, Kurreck J, Sipo I, Wang X, Pinkert S, Loschen S, Rekittke J, Weger S, Dekkers D, Vetter R, Paul M, Lamers JMJ, Poller W
Highly Efficient and Specific Modulation of Cardiac Calcium Homeostasis by Adenovector-Derived short hairpin RNA Targeting Phospholamban.
Gene Therapy 2007; 14:211-218

Sipo I §, Fechner H §, Pinkert S, Suckau L, Wang X, Weger S, Poller W (§ equal contributions)
Differential Internalization and Nuclear Uncoating of Self-Complementary AAV Pseudotype Vectors as Determinants of Transduction in Cells of
Cardiac Origin.
Gene Therapy 2007; 14: 1319-29

Riad A, Zhuo JL, Schultheiss HP and Tschoepe C
The role of the renal kallikrein-kinin system in diabetic nephropathy.
Curr Opin Nephrol Hypertens 2007; 16: 22-6

Kock K, Grube M, Jedlitschky G, Oevermann L, Siegmund W, Ritter CA, Kroemer HK.
Expression of adenosine triphosphate-binding cassette (ABC) drug transporters in peripheral blood cells: relevance for physiology and pharmacotherapy.
Clin Pharmacokinet 2007; 46: 449-470

Boisguerin P, Ay B, Radziwill G, Fritz RD, Moelling K, Volkmer R.
Characterization of a Putative Phosphorylation Switch: Adaptation of SPOT Synthesis to Analyze PDZ Domain Regulation Mechanisms.
Chembiochem 2007; 8(18): 2302-7

Westermann D, Van Linthout S, Dhayat S, Dhayat N, Schmidt A, Noutsias M, Song XY, Spillmann F, Riad A, Schultheiss HP, Tschoepe C
Tumor necrosis factor-alpha antagonism protects from myocardial inflammation and fibrosis in experimental diabetic cardiomyopathy.
Basic research in cardiology 2007; 102(6):500-507

Meissner K, Kessler W, Meyer Zu Schwabedissen HE, Schuster K, Saalfeld K, Grube M, Buck A, Jedlitschky G, Maier S, Traeger T, Mostertz J, Homuth G, Heidecke CD, Lehmann C, Kroemer HK
Sepsis affects cardiac expression of multidrug resistance protein 5 (MRP5, ABCC5), an ABC-type CGMP export pump.
Shock 2007 Nov;28(5):564-9

Wang Y, de Waard MC, Sterner-Kock A, Stepan H, Schultheiss HP, Duncker DJ, Walther T.
Cardiomyocyte-restricted over-expression of C-type natriuretic peptide prevents cardiac hypertrophy induced by myocardial infarction in mice.
Eur J Heart Fail 2007 Jun-Jul;9(6-7):548-57

Marso SP, Miller T, Rutherford BD, Gibbons RJ, Qureshi M, Kalynych A, Turco M, Schultheiss HP, Mehran R, Krucoff MW, Lansky AJ, Stone GW.
Comparison of myocardial reperfusion in patients undergoing percutaneous coronary intervention in ST-segment elevation acute myocardial infarction with versus without diabetes mellitus (from the EMERALD Trial).
Am J Cardiol 2007 Jul 15;100(2):206-10

Schubert S, Rothe D, Werk D, Grunert HP, Zeichhardt H, Erdmann VA, Kurreck J.
Strand-specific silencing of a picornavirus by RNA interference: evidence for the superiority of plus-strand specific siRNAs.
Antiviral Res 2007; 73,197-205

Voigt A, Salzmann U, Seifert U, Dathe M, Soza A, Kloetzel PM, Kuckelkorn U
20S proteasome-dependent generation of an IEpp89 murine cytomegalovirus-derived H-2L(d) epitope from a recombinant protein.
Biochem Biophys Res Commun 2007 Apr 6; 355(2):549-54

Schmidtke M, Merkle I, Klingel K, Hammerschmidt E, Zautner AE, Wutzler P.
The viral genetic background determines the outcome of coxsackievirus B3 (CVB3) infection in outbred NMRI mice.
J Med Virol 2007; 79(9):1334-42

Fechner H, Wang X, Hurtado-Picó A, Wildner J, Suckau L, Pinkert S, Sipo I, Weger S, Poller W.
A Bidirectional Tet-Dependent Promotor Construct Regulating the Expression of E1A for Tight Control of Oncolytic Adenovirus Replication.
J Biotechnol 2007; 127: 560-574

Li J, Leschka S, Rutschow S, Schwimmbeck PL, Husmann L, Noutsias M, Westermann D, Poller W, Zeichhardt H, Klingel K, Tschope C, Schultheiss HP, Pauschinger M.
Immunomodulation by interleukin-4 suppresses matrix metalloproteinases and improves cardiac function in murine myocarditis.
EurJ Pharmacol 2007;554(1): 60-68

Riad A, Du J, Stiehl S, Westermann D, Mohr S, Sobirey M, Wolfram D, Pauschinger M, Adams V, Schultheiss HP, Tschoepe C
Low-dose treatment with atorvastatin leads to antioxidative and antiinflammatory effects in diabetes mellitus.
EurJ Pharmacol 2007; Aug 27;569(3)

Noutsias M, Pauschinger M, Gross U, Lassner D, Schultheiss HP, Kuhl U
Giant-cell myocarditis in a patient presenting with dilated cardiomyopathy and ventricular tachycardias treated by immunosuppression: A case report.
Int J Cardiol. 2007, Aug 16

Goldin-Lang P, Niebergall F, Antoniak S, Szotowski B, Rosenthal P, Pels K, Schultheiss HP, Rauch U.
Ionizing radiation induces upregulation of cellular procoagulability and tissue factor expression in human peripheral blood mononuclear cells.
Thromb Res 2007;120(6):857-64

Angelow A, Schmidt M, Hoffmann W
Towards risk factor assessment in inflammatory dilated cardiomyopathy: the SFB/TR 19 study.
Eur J Cardiovasc Prev Rehabil 2007; 14(5):686-93

Kallwellis-Opara A, Dorner A, Poller WC, Noutsias M, Kuhl U, Schultheiss HP, Pauschinger M
Autoimmunological features in inflammatory cardiomyopathy.
Clin Res Cardiol 2007;96(7):469-480 (REVIEW)

Ay B, Volkmer R, Boisguerin P
Synthesis of cleavable peptides with authentic C-termini: An application for fully automated SPOT synthesis.
Tetrahedron Lett 2007; 48: 361-364

Loot AE, Roks AJM, Westermann D, Orzechowski HD, Tschöpe C, Wilschut JC, Tio RA, van Gilst WH, Hennung RH
Cardiac overexpression of human VEGF165 by recombinant Semliki Forest virus leads to adverse effects in pressure-induced heart failure.
Neth Heart J 2007: 335-341

Schultheiss HP, Kühl U, Brehm M Monographie
Kardiomyopathien
Schölmerich, ed.Medizinische Therapie: Springer; 2007

Riad A, Westermann D, Schultheiss HP, Tschoepe C
The influence of beta-adrenergic inhibition on cardiac performance in experimental myocarditis
Sociedad iberoamericana de información científica (SIIC) 2007

   
2006

Heymans S, Pauschinger M, De Palma A, Kallwellis-Opara A, Rutschow S, Swinnen M, Vanhoutte D, Gao F, Torpai R, Baker AH, Padalko E, Neyts J, Schultheiss HP, Van de Werf F, Carmeliet P, Pinto YM
Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevents cardiac injury and dysfunction during viral myocarditis.
Circulation 2006;114(6):565-573

Grube M, Meyer Zu Schwabedissen HE, Prager D, Haney J, Moritz KU, Meissner K, Rosskopf D, Eckel L, Bohm M, Jedlitschky G, Kroemer HK.
Uptake of cardiovascular drugs into the human heart: expression, regulation, and function of the carnitine transporter OCTN2 (SLC22A5).
Circulation 2006; 113: 1114-1122

Mahrholdt H, Wagner A, Deluigi CC, Kispert E, Hager S, Meinhardt G, Vogelsberg H, Dippon J, Bock CT, Klingel K, Kandolf R, Sechtem U.
Presentation, patterns of myo-cardial damage, and clinical course of viral myocarditis.
Circulation 2006; 114:1581-90 

Weinert, S., Bergmann, N., Luo, X., Erdmann, B., Gotthardt, M.
Muscle atrophy in Titin M-line deficient mice.
J Cell Biol 2006; 173(4), 559-570

Poller W, Schultheiss H-P, Kühl U.
Viruses and Other Environmental Factors as Possible Sources of Phenotypic Heterogeneity in Familial Dilated Cardiomyopathy.
JACC 2006; 47: 689-690

Grube M, Kock K, Oswald S, Draber K, Meissner K, Eckel L, Bohm M, Felix SB, Vogelgesang S, Jedlitschky G, Siegmund W, Warzok R, Kroemer HK.
Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.
Clin Pharmacol Ther 2006; 80: 607-620

Młynarczuk-Biały I, Roeckmann H, Kuckelkorn U, Schmidt B, Umbreen S, Gołab J, Ludwig A, Montag C, Wiebusch L, Hagemeier C, Schadendorf D, Kloetzel PM, Seifert U.
Combined effect of proteasome and calpain inhibition on cisplatin-resistant human melanoma cells.
Cancer Res 2006 Aug 1;66(15):7598-605

Strehl B, Joeris T, Rieger M, Visekruna A, Textoris-Taube K, Kaufmann SH, Kloetzel PM, Kuckelkorn U, Steinhoff U.
Immunoproteasomes are essential for clearance of Listeria monocytogenes in nonlymphoid tissues but not for induction of bacteria-specific CD8+ T cells.
J Immunol 2006 Nov 1; 177(9):6238-44

Nguyen LT, Song LH, Kremsner PG, Duy DN, Binh VQ, Duechting A, Kaiser H, Torresi, J Kandolf R, Bock CT.
Co-infection of human parvovirus B19 in Vietnamese patients with hepatitis B virus infection.
J Hepatol 2006; 45:361-369

Szalay G, Sauter M, Hald J, Weinzierl AO, Kandolf R, Klingel K.
Sustained NO-synthesis contributes to immunopathology in ongoing enteroviral myocarditis due to interleukin-10 disorders.
Am J Pathol 2006; 169(6): 2085-93

Szalay G, Meiners S, Voigt A, Lauber J, Spieth C, Speer N, Sauter M, Kuckelkorn U, Zell A, Klingel K, Stangl K, Kandolf R.
Ongoing coxsackievirus myocarditis is associated with increased formation and activity of myocardial immunoproteasomes.
Am J Pathol 2006; 168:1542-52

Newby AC, Pauschinger M, Spinale FG.
From tadpole tails to transgenic mice: metalloproteinases have brought about a metamorphosis in our understanding of cardiovascular disease.
Cardiovasc Res 2006;69(3):559-561

Rutschow S, Li J, Schultheiss HP, Pauschinger M.
Myocardial proteases and matrix remodeling in inflammatory heart disease.
Cardiovasc Res 2006;69(3):646-656 (REVIEW)

Horn S, Lueking A, Murphy D, Staudt A, Gutjahr C, Schulte K, Konig A, Landsberger M, Lehrach H, Felix SB, Cahill DJ.
Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease-associated protein chip.
Proteomics 2006; 6, 605-13